Comparative tachyzoite proteome analyses among six Neospora caninum isolates with different virulence
نویسندگان
چکیده
منابع مشابه
Immunogenicity of a killed whole Neospora caninum tachyzoite preparation formulated with different adjuvants.
A killed whole Neospora caninum tachyzoite preparation was formulated with various adjuvants and tested for its immunogenicity in cattle. The adjuvants used were: Havlogen, a polymer of acrylic acid cross-linked with polyallylsucrose; Polygen, a non-particulate copolymer; a mixture of Havlogen and Bay R-1005, which is a preparation of free base synthetic glycolipids; and Montanide ISA 773, a wa...
متن کاملNeospora caninum and neosporosis
Neospora caninum is a protozoan cyst forming apicomplexan parasite that causes neosporosis, notably in cattle (Bos taurus) and domestic dogs (Canis familiaris) [1,2]. It is closely related to Toxoplasma gondii and has emerged as a major cause of reproductive failure in cattle worldwide [2]. The parasite was first described in a dog with encephalomyelitis and myositis [1] and was later described...
متن کاملNeospora caninum and Wildlife
Bovine neosporosis caused by Neospora caninum is among the main causes of abortion in cattle nowadays. At present there is no effective treatment or vaccine. Serological evidence in domestic, wild, and zoo animals indicates that many species have been exposed to this parasite. However, many aspects of the life cycle of N. caninum are unknown and the role of wildlife in the life cycle of N. cani...
متن کاملComprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel Transcript Features
Toxoplasma gondii is an important protozoan parasite that infects all warm-blooded animals and causes opportunistic infections in immuno-compromised humans. Its closest relative, Neospora caninum, is an important veterinary pathogen that causes spontaneous abortion in livestock. Comparative genomics of these two closely related coccidians has been of particular interest to identify genes that c...
متن کاملProtective efficacy of vaccination with Neospora caninum multiple recombinant antigens against experimental Neospora caninum infection.
Protective efficacy of vaccination with Neospora caninum multiple recombinant antigens against N. caninum infection was evaluated in vitro and in vivo. Two major immunodominant surface antigens (NcSAG1 and NcSRS2) and two dense granule proteins (NcDG1 and NcDG2) of N. caninum tachyzoites were expressed in E. coli, respectively. An in vitro neutralization assay using polyclonal antisera raised a...
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ژورنال
عنوان ژورنال: International Journal for Parasitology
سال: 2020
ISSN: 0020-7519
DOI: 10.1016/j.ijpara.2020.02.003